Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008414-06
Application #
2162267
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1990-01-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Szwergold, Benjamin S; Lal, Sundeep (2005) Identification of diadenosine-triphosphate in mature bovine lenses. Biochem Biophys Res Commun 326:718-23
Szwergold, B S; Howell, S; Beisswenger, P J (2001) Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo. Diabetes 50:2139-47
Lal, S; Randall, W C; Taylor, A H et al. (1997) Fructose-3-phosphate production and polyol pathway metabolism in diabetic rat hearts. Metabolism 46:1333-8
Szwergold, B S; Lal, S; Taylor, A H et al. (1995) 31P-nuclear magnetic resonance evidence of an activated hexose-monophosphate shunt in hyperglycemic rat lenses in vivo. Diabetes 44:810-5
Lal, S; Szwergold, B S; Taylor, A H et al. (1995) Production of fructose and fructose-3-phosphate in maturing rat lenses. Invest Ophthalmol Vis Sci 36:969-73
Lal, S; Szwergold, B S; Taylor, A H et al. (1995) Metabolism of fructose-3-phosphate in the diabetic rat lens. Arch Biochem Biophys 318:191-9
Kappler, F; Su, B; Szwergold, B S et al. (1995) Identification of galactitol 2-phosphate and galactitol 3-phosphate in the lens of galactose-fed rats. Metabolism 44:1527-31
Lal, S; Szwergold, B S; Kappler, F et al. (1994) Effect of pH on the bioenergetics of perfused porcine lenses. Curr Eye Res 13:239-42
Lal, S; Szwergold, B S; Kappler, F et al. (1993) Detection of fructose-3-phosphokinase activity in intact mammalian lenses by 31P NMR spectroscopy. J Biol Chem 268:7763-7
Petersen, A; Kappler, F; Szwergold, B S et al. (1992) Fructose metabolism in the human erythrocyte. Phosphorylation to fructose 3-phosphate. Biochem J 284 ( Pt 2):363-6

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