Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY008972-04S1
Application #
2162598
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1991-02-01
Project End
1995-06-30
Budget Start
1994-02-01
Budget End
1995-06-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Washington University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Griffith, Thomas S; Kazama, Hirotaka; VanOosten, Rebecca L et al. (2007) Apoptotic cells induce tolerance by generating helpless CD8+ T cells that produce TRAIL. J Immunol 178:2679-87
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Apte, Rajendra S; Richter, Jennifer; Herndon, John et al. (2006) Macrophages inhibit neovascularization in a murine model of age-related macular degeneration. PLoS Med 3:e310
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Herndon, John M; Stuart, Patrick M; Ferguson, Thomas A (2005) Peripheral deletion of antigen-specific T cells leads to long-term tolerance mediated by CD8+ cytotoxic cells. J Immunol 174:4098-104
Ferguson, Thomas A; Stuart, Patrick M; Herndon, John M et al. (2003) Apoptosis, tolerance, and regulatory T cells--old wine, new wineskins. Immunol Rev 193:111-23
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Lee, Hae-Ock; Herndon, John M; Barreiro, Ramon et al. (2002) TRAIL: a mechanism of tumor surveillance in an immune privileged site. J Immunol 169:4739-44
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Kaplan, H J; Leibole, M A; Tezel, T et al. (1999) Fas ligand (CD95 ligand) controls angiogenesis beneath the retina. Nat Med 5:292-7

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