Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009391-04
Application #
2163010
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1992-01-01
Project End
1995-06-30
Budget Start
1995-01-01
Budget End
1995-06-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Harper, Angelica R; Le, Anh T; Mather, Timothy et al. (2018) Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem 26:5766-5779
Harper, Angelica R; Wang, Xiang; Moiseyev, Gennadiy et al. (2016) Postnatal Chick Choroids Exhibit Increased Retinaldehyde Dehydrogenase Activity During Recovery From Form Deprivation Induced Myopia. Invest Ophthalmol Vis Sci 57:4886-4897
Summers, Jody A; Harper, Angelica R; Feasley, Christa L et al. (2016) Identification of Apolipoprotein A-I as a Retinoic Acid-binding Protein in the Eye. J Biol Chem 291:18991-9005
Harper, Angelica R; Wiechmann, Allan F; Moiseyev, Gennadiy et al. (2015) Identification of active retinaldehyde dehydrogenase isoforms in the postnatal human eye. PLoS One 10:e0122008
Harper, Angelica R; Summers, Jody A (2015) The dynamic sclera: extracellular matrix remodeling in normal ocular growth and myopia development. Exp Eye Res 133:100-11
Summers, Jody A (2013) The choroid as a sclera growth regulator. Exp Eye Res 114:120-7
Rada, Jody A Summers; Hollaway, Lindsey R; Lam, Wengtse et al. (2012) Identification of RALDH2 as a visually regulated retinoic acid synthesizing enzyme in the chick choroid. Invest Ophthalmol Vis Sci 53:1649-62
Summers Rada, Jody A; Hollaway, Lindsey R (2011) Regulation of the biphasic decline in scleral proteoglycan synthesis during the recovery from induced myopia. Exp Eye Res 92:394-400
Rada, Jody A Summers; Wiechmann, Allan F; Hollaway, Lindsey R et al. (2010) Increased hyaluronan synthase-2 mRNA expression and hyaluronan accumulation with choroidal thickening: response during recovery from induced myopia. Invest Ophthalmol Vis Sci 51:6172-9
Wiechmann, Allan F; Hollaway, Lindsey R; Rada, Jody A Summers (2009) Melatonin receptor expression in Xenopus laevis surface corneal epithelium: diurnal rhythm of lateral membrane localization. Mol Vis 15:2384-403

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