Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY009747-05
Application #
2163472
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Kumar, Rajesh; Eastwood, Amy L; Brown, Milton L et al. (2002) Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation. J Mol Biol 319:593-602
Faisal Khan, K M; Laurie, Gordon W; McCaffrey, Timothy A et al. (2002) Exposure of cryptic domains in the alpha 1-chain of laminin-1 by elastase stimulates macrophages urokinase and matrix metalloproteinase-9 expression. J Biol Chem 277:13778-86
Sanghi, S; Kumar, R; Lumsden, A et al. (2001) cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland. J Mol Biol 310:127-39
Sanghi, S; Kumar, R; Walton, S et al. (2000) Quantitation of rat lacrimal secretion: a novel sandwich ELISA with high sensitivity. Exp Eye Res 70:651-8
Kumar, R; Lumsden, A; Ciclitira, P J et al. (2000) Human genome search in celiac disease using gliadin cDNA as probe. J Mol Biol 300:1155-67
Chen, L; Glass, J D; Walton, S C et al. (1998) Role of laminin-1, collagen IV, and an autocrine factor(s) in regulated secretion by lacrimal acinar cells. Am J Physiol 275:C278-84
Laurie, G W; Glass, J D; Ogle, R A et al. (1996) ""BM180"": a novel basement membrane protein with a role in stimulus-secretion coupling by lacrimal acinar cells. Am J Physiol 270:C1743-50
Matter, M L; Laurie, G W (1996) A putative sub-10-kDa basement membrane activity required for lung alveolar formation in vitro. Am J Physiol 271:L489-94
Laurie, G W; Ciclitira, P J; Ellis, H J et al. (1995) Immunological and partial sequence identity of mouse BM180 with wheat alpha-gliadin. Biochem Biophys Res Commun 217:10-5
Laurie, G W; Stone, C M; Glass, J D (1994) Serum-free primary culture of harderian acinar cells. Exp Eye Res 58:375-8

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