Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY010138-09
Application #
2163841
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1993-03-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Fisher, S; Genbacev, O; Maidji, E et al. (2000) Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis. J Virol 74:6808-20
Tugizov, S; Maidji, E; Xiao, J et al. (1999) An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membrane. J Virol 73:8677-88
Tugizov, S; Maidji, E; Xiao, J et al. (1998) Human cytomegalovirus glycoprotein B contains autonomous determinants for vectorial targeting to apical membranes of polarized epithelial cells. J Virol 72:7374-86
Maidji, E; Tugizov, S; Abenes, G et al. (1998) A novel human cytomegalovirus glycoprotein, gpUS9, which promotes cell-to-cell spread in polarized epithelial cells, colocalizes with the cytoskeletal proteins E-cadherin and F-actin. J Virol 72:5717-27
Navarro, D; Lennette, E; Tugizov, S et al. (1997) Humoral immune response to functional regions of human cytomegalovirus glycoprotein B. J Med Virol 52:451-9
Zheng, Z; Maidji, E; Tugizov, S et al. (1996) Mutations in the carboxyl-terminal hydrophobic sequence of human cytomegalovirus glycoprotein B alter transport and protein chaperone binding. J Virol 70:8029-40
Maidji, E; Tugizov, S; Jones, T et al. (1996) Accessory human cytomegalovirus glycoprotein US9 in the unique short component of the viral genome promotes cell-to-cell transmission of virus in polarized epithelial cells. J Virol 70:8402-10
Tugizov, S; Maidji, E; Pereira, L (1996) Role of apical and basolateral membranes in replication of human cytomegalovirus in polarized retinal pigment epithelial cells. J Gen Virol 77 ( Pt 1):61-74
Ramakrishnan, M; Tugizov, S; Pereira, L et al. (1995) Conformation-defective herpes simplex virus 1 glycoprotein B activates the promoter of the grp94 gene that codes for the 94-kD stress protein in the endoplasmic reticulum. DNA Cell Biol 14:373-84
Tugizov, S; Wang, Y; Qadri, I et al. (1995) Mutated forms of human cytomegalovirus glycoprotein B are impaired in inducing syncytium formation. Virology 209:580-91

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