Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY010722-02
Application #
2164788
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1995-03-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Pharmacology
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Roberts, J E; Finley, E L; Patat, S A et al. (2001) Photooxidation of lens proteins with xanthurenic acid: a putative chromophore for cataractogenesis. Photochem Photobiol 74:740-4
Schey, K L; Little, M; Fowler, J G et al. (2000) Characterization of human lens major intrinsic protein structure. Invest Ophthalmol Vis Sci 41:175-82
Schey, K L; Finley, E L (2000) Identification of peptide oxidation by tandem mass spectrometry. Acc Chem Res 33:299-306
Schey, K L; Patat, S; Chignell, C F et al. (2000) Photooxidation of lens alpha-crystallin by hypericin (active ingredient in St. John's Wort). Photochem Photobiol 72:200-3
Schey, K L; Fowler, J G; Shearer, T R et al. (1999) Modifications to rat lens major intrinsic protein in selenite-induced cataract. Invest Ophthalmol Vis Sci 40:657-67
Finley, E L; Dillon, J; Crouch, R K et al. (1998) Radiolysis-induced oxidation of bovine alpha-crystallin. Photochem Photobiol 68:9-15
Finley, E L; Dillon, J; Crouch, R K et al. (1998) Identification of tryptophan oxidation products in bovine alpha-crystallin. Protein Sci 7:2391-7
Finley, E L; Busman, M; Dillon, J et al. (1997) Identification of photooxidation sites in bovine alpha-crystallin. Photochem Photobiol 66:635-41
Schey, K L; Fowler, J G; Schwartz, J C et al. (1997) Complete map and identification of the phosphorylation site of bovine lens major intrinsic protein. Invest Ophthalmol Vis Sci 38:2508-15
Swamy-Mruthinti, S; Schey, K L (1997) Mass spectroscopic identification of in vitro glycated sites of MIP. Curr Eye Res 16:936-41