Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY011632-04
Application #
6138203
Study Section
Visual Sciences C Study Section (VISC)
Program Officer
Hunter, Chyren
Project Start
1997-01-01
Project End
2001-12-31
Budget Start
2000-01-01
Budget End
2000-12-31
Support Year
4
Fiscal Year
2000
Total Cost
$263,956
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Tapon, Nicolas; Harvey, Kieran F; Bell, Daphne W et al. (2002) salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell 110:467-78
Tseng, Ai-Sun Kelly; Hariharan, Iswar K (2002) An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. Genetics 162:229-43
Bernards, A; Hariharan, I K (2001) Of flies and men--studying human disease in Drosophila. Curr Opin Genet Dev 11:274-8
Tapon, N; Moberg, K H; Hariharan, I K (2001) The coupling of cell growth to the cell cycle. Curr Opin Cell Biol 13:731-7
Tapon, N; Ito, N; Dickson, B J et al. (2001) The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105:345-55
Fortini, M E; Skupski, M P; Boguski, M S et al. (2000) A survey of human disease gene counterparts in the Drosophila genome. J Cell Biol 150:F23-30
de Nooij, J C; Graber, K H; Hariharan, I K (2000) Expression of the cyclin-dependent kinase inhibitor Dacapo is regulated by cyclin E. Mech Dev 97:73-83
Li, Q; Hariharan, I K; Chen, F et al. (1997) Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development. Proc Natl Acad Sci U S A 94:12515-20