Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY012961-04
Application #
6635694
Study Section
Visual Sciences A Study Section (VISA)
Program Officer
Shen, Grace L
Project Start
2000-05-01
Project End
2004-07-31
Budget Start
2003-05-01
Budget End
2004-07-31
Support Year
4
Fiscal Year
2003
Total Cost
$286,000
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Tang, Aihua; Caballero, Armando R; Marquart, Mary E et al. (2013) Pseudomonas aeruginosa small protease (PASP), a keratitis virulence factor. Invest Ophthalmol Vis Sci 54:2821-8
Tang, Aihua; Marquart, Mary E; Fratkin, Jonathan D et al. (2009) Properties of PASP: a Pseudomonas protease capable of mediating corneal erosions. Invest Ophthalmol Vis Sci 50:3794-801
McCormick, C C; Hobden, J A; Balzli, C L et al. (2007) Surfactant protein D in Pseudomonas aeruginosa keratitis. Ocul Immunol Inflamm 15:371-9
Thibodeaux, Brett A; Caballero, Armando R; Marquart, Mary E et al. (2007) Corneal virulence of Pseudomonas aeruginosa elastase B and alkaline protease produced by Pseudomonas putida. Curr Eye Res 32:373-86
Malloy, Jaret L; Veldhuizen, Ruud A W; Thibodeaux, Brett A et al. (2005) Pseudomonas aeruginosa protease IV degrades surfactant proteins and inhibits surfactant host defense and biophysical functions. Am J Physiol Lung Cell Mol Physiol 288:L409-18
Thibodeaux, Brett A; Caballero, Armando R; Dajcs, Joseph J et al. (2005) Pseudomonas aeruginosa protease IV: a corneal virulence factor of low immunogenicity. Ocul Immunol Inflamm 13:169-82
Marquart, Mary E; Caballero, Armando R; Chomnawang, Mullika et al. (2005) Identification of a novel secreted protease from Pseudomonas aeruginosa that causes corneal erosions. Invest Ophthalmol Vis Sci 46:3761-8
Marquart, Mary E; Dajcs, Joseph J; Caballero, Armando R et al. (2005) Calcium and magnesium enhance the production of Pseudomonas aeruginosa protease IV, a corneal virulence factor. Med Microbiol Immunol 194:39-45
Caballero, Armando; Thibodeaux, Brett; Marquart, Mary et al. (2004) Pseudomonas keratitis: protease IV gene conservation, distribution, and production relative to virulence and other Pseudomonas proteases. Invest Ophthalmol Vis Sci 45:522-30
Thibodeaux, Brett A; Dajcs, Joseph J; Caballero, Armando R et al. (2004) Quantitative comparison of fluoroquinolone therapies of experimental gram-negative bacterial keratitis. Curr Eye Res 28:337-42

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