Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM013956-31
Application #
2168809
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1979-03-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1998-02-28
Support Year
31
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Faraldos, Juan A; Coates, Robert M; Giner, José-Luis (2013) Alternative synthesis of the Colorado potato beetle pheromone. J Org Chem 78:10548-54
Faraldos, Juan A; Kariuki, Benson M; Coates, Robert M (2011) 2-azapinanes: aza analogues of the enantiomeric pinyl carbocation intermediates in pinene biosynthesis. Org Lett 13:836-9
Köksal, Mustafa; Jin, Yinghua; Coates, Robert M et al. (2011) Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis. Nature 469:116-20
Faraldos, Juan A; Wu, Shuiqin; Chappell, Joe et al. (2010) Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-(2)H(1)]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. J Am Chem Soc 132:2998-3008
Faraldos, Juan A; O'Maille, Paul E; Dellas, Nikki et al. (2010) Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate. J Am Chem Soc 132:4281-9
Mann, Francis M; Prisic, Sladjana; Hu, Huayou et al. (2009) Characterization and inhibition of a class II diterpene cyclase from Mycobacterium tuberculosis: implications for tuberculosis. J Biol Chem 284:23574-9
Hu, Huayou; Faraldos, Juan A; Coates, Robert M (2009) Scope and mechanism of intramolecular aziridination of cyclopent-3-enyl-methylamines to 1-azatricyclo[2.2.1.0(2,6)]heptanes with lead tetraacetate. J Am Chem Soc 131:11998-2006
Faraldos, Juan A; Wu, Shuiqin; Chappell, Joe et al. (2007) Conformational Analysis of (+)-Germacrene A by Variable Temperature NMR and NOE Spectroscopy. Tetrahedron 63:7733-7742