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Kline, P C; Schramm, V L (1994) Electrostatic potential surfaces of the transition state for AMP deaminase and for (R)-coformycin, a transition state inhibitor. J Biol Chem 269:22385-90
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Ehrlich, J I; Schramm, V L (1994) Electrostatic potential surface analysis of the transition state for AMP nucleosidase and for formycin 5'-phosphate, a transition-state inhibitor. Biochemistry 33:8890-6
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Schramm, V L; Horenstein, B A; Kline, P C (1994) Transition state analysis and inhibitor design for enzymatic reactions. J Biol Chem 269:18259-62
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Sollitti, P; Merkler, D J; Estupinan, B et al. (1993) Yeast AMP deaminase. Catalytic activity in Schizosaccharomyces pombe and chromosomal location in Saccharomyces cerevisiae. J Biol Chem 268:4549-55
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Merkler, D J; Schramm, V L (1993) Catalytic mechanism of yeast adenosine 5'-monophosphate deaminase. Zinc content, substrate specificity, pH studies, and solvent isotope effects. Biochemistry 32:5792-9
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Merkler, D J; Kline, P C; Weiss, P et al. (1993) Transition-state analysis of AMP deaminase. Biochemistry 32:12993-3001
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Horenstein, B A; Schramm, V L (1993) Correlation of the molecular electrostatic potential surface of an enzymatic transition state with novel transition-state inhibitors. Biochemistry 32:9917-25
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Horenstein, B A; Schramm, V L (1993) Electronic nature of the transition state for nucleoside hydrolase. A blueprint for inhibitor design. Biochemistry 32:7089-97
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Kline, P C; Schramm, V L (1992) Purine nucleoside phosphorylase. Inosine hydrolysis, tight binding of the hypoxanthine intermediate, and third-the-sites reactivity. Biochemistry 31:5964-73
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Horenstein, B A; Parkin, D W; Estupinan, B et al. (1991) Transition-state analysis of nucleoside hydrolase from Crithidia fasciculata. Biochemistry 30:10788-95
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