Abstract

Our long-term goal continues to be to design and evaluate clinically a polymeric biodegradable membrane which can be used to treat full-thickness skin wounds in patients with extreme skin loss. Our objectives for the coming year are a) continuation of ultrastructural studies of Stage 2 grafts on guinea pigs in the immediate post-grafting period, 3-21 days post-grafting b) continue human trials of Stage 2 membranes and c) complete the study of the effect of graft degradation rate and pore size on wound contraction rate of guinea pig wounds.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM023946-11
Application #
3271976
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1977-04-01
Project End
1989-03-31
Budget Start
1987-04-01
Budget End
1989-03-31
Support Year
11
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Type
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139