Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026757-09
Application #
3274184
Study Section
Genetics Study Section (GEN)
Project Start
1979-08-01
Project End
1989-08-31
Budget Start
1989-04-01
Budget End
1989-08-31
Support Year
9
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Carnegie-Mellon University
Department
Type
Schools of Arts and Sciences
DUNS #
052184116
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Chen, X; Reynolds, E R; Ranganayakulu, G et al. (1994) A maternal product of the Punch locus of Drosophila melanogaster is required for precellular blastoderm nuclear divisions. J Cell Sci 107 ( Pt 12):3501-13
O'Donnell, J M; Ranganayakulu, G; Chen, X et al. (1993) Drosophila GTP cyclohydrodrolase: multiple isoform products of a single gene derive from alternate transcripts that are developmentally regulated and functionally specific. Adv Exp Med Biol 338:147-55
McLean, J R; Krishnakumar, S; O'Donnell, J M (1993) Multiple mRNAs from the Punch locus of Drosophila melanogaster encode isoforms of GTP cyclohydrolase I with distinct N-terminal domains. J Biol Chem 268:27191-7
McLean, J R; Boswell, R; O'Donnell, J (1990) Cloning and molecular characterization of a metabolic gene with development functions in Drosophila. I. Analysis of the head function of Punch. Genetics 126:1007-19
O'Donnell, J; Boswell, R; Reynolds, T et al. (1989) A cytogenetic analysis of the Punch-tudor region of chromosome 2R in Drosophila melanogaster. Genetics 121:273-80
O'Donnell, J M; McLean, J R; Reynolds, E R (1989) Molecular and developmental genetics of the Punch locus, a pterin biosynthesis gene in Drosophila melanogaster. Dev Genet 10:273-86
Reynolds, E R; O'Donnell, J M (1988) Characterization of new Punch mutations: identification of two additional mutant classes. Genetics 119:609-17
Reynolds, E R; O'Donnell, J M (1987) An analysis of the embryonic defects in Punch mutants of Drosophila melanogaster. Dev Biol 123:430-41
Weisberg, E P; O'Donnell, J M (1986) Purification and characterization of GTP cyclohydrolase I from Drosophila melanogaster. J Biol Chem 261:1453-8
Mackay, W J; Reynolds, E R; O'Donnell, J M (1985) Tissue-specific and complex complementation patterns in the Punch locus of Drosophila melanogaster. Genetics 111:885-904