The proposed research involves the development of new organoselenium reagents which effect important synthetic transformations in ways which are superior to currently available procedures. These newly-developed procedures will be used as the key steps in the syntheses of a number of biologically-importnt compounds. Finally we plan to synthesize a large variety of organoselenium compounds which can be tested for biological activity.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM026908-06
Application #
3274375
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1979-07-01
Project End
1986-03-31
Budget Start
1985-04-01
Budget End
1986-03-31
Support Year
6
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Emory University
Department
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
MacMurray, A J; Bell, J I; Denney Jr, D et al. (1987) Molecular mapping class II polymorphisms in the human major histocompatibility complex. II. DQ beta. J Immunol 139:574-86
Bell, J I; Denney Jr, D; MacMurray, A et al. (1987) Molecular mapping of class II polymorphisms in the human major histocompatibility complex. I. DR beta. J Immunol 139:562-73