Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM028226-14
Application #
2175141
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1980-07-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston University
Department
Type
Schools of Arts and Sciences
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Saraceni-Richards, C A; Jacobson, G R (1997) A conserved glutamate residue, Glu-257, is important for substrate binding and transport by the Escherichia coli mannitol permease. J Bacteriol 179:1135-42
Saraceni-Richards, C A; Jacobson, G R (1997) Subunit and amino acid interactions in the Escherichia coli mannitol permease: a functional complementation study of coexpressed mutant permease proteins. J Bacteriol 179:5171-7
Begley, G S; Warner, K A; Arents, J C et al. (1996) Isolation and characterization of a mutation that alters the substrate specificity of the Escherichia coli glucose permease. J Bacteriol 178:940-2
Begley, G S; Jacobson, G R (1994) Overexpression, phosphorylation, and growth effects of ORF162, a Klebsiella pneumoniae protein that is encoded by a gene linked to rpoN, the gene encoding sigma 54. FEMS Microbiol Lett 119:389-94
Postma, P W; Lengeler, J W; Jacobson, G R (1993) Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 57:543-94
Jacobson, G R; Saraceni-Richards, C (1993) The Escherichia coli mannitol permease as a model for transport via the bacterial phosphotransferase system. J Bioenerg Biomembr 25:621-6
Weng, Q P; Jacobson, G R (1993) Role of a conserved histidine residue, His-195, in the activities of the Escherichia coli mannitol permease. Biochemistry 32:11211-6
Briggs, C E; Khandekar, S S; Jacobson, G R (1992) Structure/function relationships in the Escherichia coli mannitol permease: identification of regions important for membrane insertion, substrate binding and oligomerization. Res Microbiol 143:139-49
Weng, Q P; Elder, J; Jacobson, G R (1992) Site-specific mutagenesis of residues in the Escherichia coli mannitol permease that have been suggested to be important for its phosphorylation and chemoreception functions. J Biol Chem 267:19529-35
Sugiyama, J E; Mahmoodian, S; Jacobson, G R (1991) Membrane topology analysis of Escherichia coli mannitol permease by using a nested-deletion method to create mtlA-phoA fusions. Proc Natl Acad Sci U S A 88:9603-7

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