Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM028521-23
Application #
6635855
Study Section
Special Emphasis Panel (ZRG1-CDF-3 (01))
Program Officer
Shapiro, Bert I
Project Start
1988-04-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
23
Fiscal Year
2003
Total Cost
$342,620
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
781613492
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Gerace, Larry; Tapia, Olga (2018) Messages from the voices within: regulation of signaling by proteins of the nuclear lamina. Curr Opin Cell Biol 52:14-21
Stroud, Matthew J; Fang, Xi; Zhang, Jianlin et al. (2018) Luma is not essential for murine cardiac development and function. Cardiovasc Res 114:378-388
Stroud, Matthew J; Feng, Wei; Zhang, Jianlin et al. (2017) Nesprin 1?2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle. J Cell Biol 216:1915-1924
Tapia, Olga; Gerace, Larry (2016) Analysis of Nuclear Lamina Proteins in Myoblast Differentiation by Functional Complementation. Methods Mol Biol 1411:177-94
Tapia, Olga; Fong, Loren G; Huber, Michael D et al. (2015) Nuclear envelope protein Lem2 is required for mouse development and regulates MAP and AKT kinases. PLoS One 10:e0116196
Huber, Michael D; Vesely, Paul W; Datta, Kaustuv et al. (2013) Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis. J Cell Biol 203:427-36
Kerkow, Donald E; Carmel, Andrew B; Menichelli, Elena et al. (2012) The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold. J Mol Biol 415:649-65
Gerace, Larry; Huber, Michael D (2012) Nuclear lamina at the crossroads of the cytoplasm and nucleus. J Struct Biol 177:24-31
Hintersteiner, Martin; Ambrus, Géza; Bednenko, Janna et al. (2010) Identification of a small molecule inhibitor of importin ? mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries. ACS Chem Biol 5:967-79
Ambrus, Geza; Whitby, Landon R; Singer, Eric L et al. (2010) Small molecule peptidomimetic inhibitors of importin ýý/ýý mediated nuclear transport. Bioorg Med Chem 18:7611-20

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