Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM029356-14
Application #
2175474
Study Section
Molecular Cytology Study Section (CTY)
Project Start
1981-09-29
Project End
1998-12-31
Budget Start
1996-07-01
Budget End
1998-12-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Kapadia, Fehmida; Pryor, Anne; Chang, Tien-Hsien et al. (2006) Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49. Gene 384:37-44
Yang, Z; Cloud, A; Hughes, D et al. (2006) Stable inhibition of human thymidylate synthase expression following retroviral introduction of an siRNA gene. Cancer Gene Ther 13:107-14
Kapadia, Fehmida; Johnson, Lee F (2006) Introduction of an initiator element in the mouse thymidylate synthase promoter alters S phase regulation but has no effect on promoter bidirectionality. J Cell Biochem 97:599-608
Pryor, Anne; Tung, Luh; Yang, Zhe et al. (2004) Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Nucleic Acids Res 32:1857-65
Rudge, Thomas L; Johnson, Lee F (2002) Synergistic activation of the TATA-less mouse thymidylate synthase promoter by the Ets transcription factor GABP and Sp1. Exp Cell Res 274:45-55
Gribaudo, Giorgio; Riera, Ludovica; Rudge, Thomas L et al. (2002) Human cytomegalovirus infection induces cellular thymidylate synthase gene expression in quiescent fibroblasts. J Gen Virol 83:2983-93
Gribaudo, G; Riera, L; Lembo, D et al. (2001) The anticytomegaloviral activity of raltitrexed is abrogated in quiescent mouse fibroblasts that overexpress thymidylate synthase. Virus Res 73:57-65
Dong, S; Lester, L; Johnson, L F (2000) Transcriptional control elements and complex initiation pattern of the TATA-less bidirectional human thymidylate synthase promoter. J Cell Biochem 77:50-64
Gribaudo, G; Riera, L; Lembo, D et al. (2000) Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication. J Virol 74:4979-87
Lee, Y; Johnson, L F (2000) Transcriptional control elements of the rat thymidylate synthase promoter: evolutionary conservation of regulatory features. Exp Cell Res 258:53-64

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