Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM029536-11S1
Application #
3277191
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1981-04-01
Project End
1993-03-31
Budget Start
1989-03-01
Budget End
1989-03-31
Support Year
11
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Harden, T Kendall; Sondek, John (2006) Regulation of phospholipase C isozymes by ras superfamily GTPases. Annu Rev Pharmacol Toxicol 46:355-79
Seifert, Jason P; Snyder, Jason T; Sondek, John et al. (2006) Direct activation of purified phospholipase C epsilon by RhoA studied in reconstituted phospholipid vesicles. Methods Enzymol 406:260-71
Bourdon, David M; Wing, Michele R; Edwards, Earl B et al. (2006) Quantification of isozyme-specific activation of phospholipase C-beta2 by Rac GTPases and phospholipase C-epsilon by Rho GTPases in an intact cell assay system. Methods Enzymol 406:489-99
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Wing, M R; Houston, D; Kelley, G G et al. (2001) Activation of phospholipase C-epsilon by heterotrimeric G protein betagamma-subunits. J Biol Chem 276:48257-61
Cunningham, M L; Waldo, G L; Hollinger, S et al. (2001) Protein kinase C phosphorylates RGS2 and modulates its capacity for negative regulation of Galpha 11 signaling. J Biol Chem 276:5438-44

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