Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM030509-09
Application #
3278305
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1982-05-01
Project End
1990-06-30
Budget Start
1990-05-01
Budget End
1990-06-30
Support Year
9
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Shi, W; Hoganson, C W; Espe, M et al. (2000) Electron paramagnetic resonance and electron nuclear double resonance spectroscopic identification and characterization of the tyrosyl radicals in prostaglandin H synthase 1. Biochemistry 39:4112-21
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Tsai, A l; Wei, C; Baek, H K et al. (1997) Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX. J Biol Chem 272:8885-94
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Kulmacz, R J; Palmer, G; Wei, C et al. (1994) Reaction and free radical kinetics of prostaglandin H synthase with manganese protoporphyrin IX as the prosthetic group. Biochemistry 33:5428-39
Kulmacz, R J; Pendleton, R B; Lands, W E (1994) Interaction between peroxidase and cyclooxygenase activities in prostaglandin-endoperoxide synthase. Interpretation of reaction kinetics. J Biol Chem 269:5527-36
Ruan, K H; Kulmacz, R J; Wilson, A et al. (1993) Highly sensitive fluorimetric enzyme immunoassay for prostaglandin H synthase solubilized from cultured cells. J Immunol Methods 162:23-30
Kulmacz, R J; Palmer, G; Tsai, A L (1993) Substrate-induced free radicals in prostaglandin H synthase. J Lipid Mediat 6:145-54

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