Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM030822-09
Application #
3278713
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1983-01-01
Project End
1991-08-18
Budget Start
1991-01-01
Budget End
1991-08-18
Support Year
9
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Amirhaeri, S; Wohlrab, F; Wells, R D (1995) Differential effects of simple repeating DNA sequences on gene expression from the SV40 early promoter. J Biol Chem 270:3313-9
Klysik, J (1995) An intramolecular triplex structure from non-mirror repeated sequence containing both Py:Pu.Py and Pu:Pu.Py triads. J Mol Biol 245:499-507
Kang, S; Jaworski, A; Ohshima, K et al. (1995) Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli. Nat Genet 10:213-8
Kang, S; Wells, R D (1994) Zinc destabilizes DNA Watson-Crick pairs at AGCT. J Biol Chem 269:9528-32
Wang, Y H; Amirhaeri, S; Kang, S et al. (1994) Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene. Science 265:669-71
Lukomski, S; Wells, R D (1994) Left-handed Z-DNA and in vivo supercoil density in the Escherichia coli chromosome. Proc Natl Acad Sci U S A 91:9980-4
Klysik, J; Shimizu, M (1993) Escherichia coli single-stranded DNA-binding protein alters the structure of intramolecular triplexes in plasmids. FEBS Lett 333:261-7
Kang, S; Wohlrab, F; Wells, R D (1992) GC-rich flanking tracts decrease the kinetics of intramolecular DNA triplex formation. J Biol Chem 267:19435-42
Rahmouni, A R; Wells, R D (1992) Direct evidence for the effect of transcription on local DNA supercoiling in vivo. J Mol Biol 223:131-44
Klysik, J (1992) Cruciform extrusion facilitates intramolecular triplex formation between distal oligopurine.oligopyrimidine tracts: long range effects. J Biol Chem 267:17430-7

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