This project aims to characterize direct interactions between RNA molecules and bilayer membranes, and to manipulate these interactions for experimental purposes. As a consequence of these studies, such interactions will be sought in cells. In addition, this this project proposes to find and characterize new classes of RNA enzymes that use enzymatic cofactors as and intrinsic part of their reaction mechanisms.
Janas, Teresa; Janas, Tadeusz; Yarus, Michael (2012) Human tRNA(Sec) associates with HeLa membranes, cell lipid liposomes, and synthetic lipid bilayers. RNA 18:2260-8 |
Smit, Sandra; Yarus, Michael; Knight, Rob (2006) Natural selection is not required to explain universal compositional patterns in rRNA secondary structure categories. RNA 12:1-14 |
Janas, Tadeusz; Janas, Teresa; Yarus, Michael (2006) Specific RNA binding to ordered phospholipid bilayers. Nucleic Acids Res 34:2128-36 |
Knight, Rob; De Sterck, Hans; Markel, Rob et al. (2005) Abundance of correctly folded RNA motifs in sequence space, calculated on computational grids. Nucleic Acids Res 33:5924-35 |
Janas, Teresa; Janas, Tadeusz; Yarus, Michael (2004) A membrane transporter for tryptophan composed of RNA. RNA 10:1541-9 |
Janas, Tadeusz; Yarus, Michael (2003) Visualization of membrane RNAs. RNA 9:1353-61 |
Jadhav, Vasant R; Yarus, Michael (2002) Coenzymes as coribozymes. Biochimie 84:877-88 |
Illangasekare, Mali; Yarus, Michael (2002) Phenylalanine-binding RNAs and genetic code evolution. J Mol Evol 54:298-311 |
Jadhav, Vasant R; Yarus, Michael (2002) Acyl-CoAs from coenzyme ribozymes. Biochemistry 41:723-9 |
Kumar, R K; Yarus, M (2001) RNA-catalyzed amino acid activation. Biochemistry 40:6998-7004 |
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