Abstract

The proposed research is designed: (1) to determine the amounts and kinds of genetic variability that can be detected in higher organisms using restriction enzymes and molecularly cloned DNA probes; and (2) to utilize the information gained to study the evolutionary genetics of a species complex at the population, interspecific, and intergeneric levels. The basic materials will include two experimental plant populations which are particularly useful for this study because many aspects of their population genetics and evolution have already been characterized in terms of allozymes, morphological polymorphisms, measurement characters and disease reaction. Thus, the proposed molecular genetic research will be integrated with a detailed long-term study of fundamental genetic mechanisms and evolutionary processes. This integration of molecular genetics with population and evolutionary genetics is expected to contribute significantly to basic biological research and so to health-related research.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032429-02
Application #
3281243
Study Section
Genetics Study Section (GEN)
Project Start
1984-03-01
Project End
1987-02-28
Budget Start
1985-03-01
Budget End
1986-02-28
Support Year
2
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of California Davis
Department
Type
Earth Sciences/Resources
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Allard, R W; Garcia, P; Saenz-de-Miera, L E et al. (1993) Evolution of multilocus genetic structure in Avena hirtula and Avena barbata. Genetics 135:1125-39
Garcia, P; Morris, M I; Saenz-de-Miera, L E et al. (1991) Genetic diversity and adaptedness in tetraploid Avena barbata and its diploid ancestors Avena hirtula and Avena wiestii. Proc Natl Acad Sci U S A 88:1207-11
Perez de la Vega, M; Garcia, P; Allard, R W (1991) Multilocus genetic structure of ancestral Spanish and colonial Californian populations of Avena barbata. Proc Natl Acad Sci U S A 88:1202-6
Wagner, D B; Allard, R W (1991) Pollen migration in predominantly self-fertilizing plants: barley. J Hered 82:302-4
Allard, R W; Saghai Maroof, M A; Zhang, Q et al. (1990) Genetic and molecular organization of ribosomal DNA (rDNA) variants in wild and cultivated barley. Genetics 126:743-51
Zhang, Q F; Saghai Maroof, M A; Allard, R W (1990) Effects on adaptedness of variations in ribosomal DNA copy number in populations of wild barley (Hordeum vulgare ssp. spontaneum). Proc Natl Acad Sci U S A 87:8741-5
Saghai Maroof, M A; Allard, R W; Zhang, Q F (1990) Genetic diversity and ecogeographical differentiation among ribosomal DNA alleles in wild and cultivated barley. Proc Natl Acad Sci U S A 87:8486-90
Garcia, P; Vences, F J; Perez de la Vega, M et al. (1989) Allelic and genotypic composition of ancestral Spanish and colonial Californian gene pools of Avena barbata: evolutionary implications. Genetics 122:687-94
McDonald, B A; McDermott, J M; Allard, R W et al. (1989) Coevolution of host and pathogen populations in the Hordeum vulgare-Rhynchosporium secalis pathosystem. Proc Natl Acad Sci U S A 86:3924-7
McDermott, J M; McDonald, B A; Allard, R W et al. (1989) Genetic variability for pathogenicity, isozyme, ribosomal DNA and colony color variants in populations of Rhynchosporium secalis. Genetics 122:561-5

Showing the most recent 10 out of 13 publications