This proposal details a methodological study into the synthetic applications of furan-carbonyl photocycloadditions. These studies serve two major purposes. First they would provide new information on the photocycloaddition reaction including the stereochemical consequences of what amounts to a threo specific aldolization process. Second, they would illustrate the design of systems which could fully exploit the usefulness of these reactions in the synthesis of a large body of biologically important natural products.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032527-03
Application #
3281449
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1983-07-01
Project End
1987-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code