Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032707-12
Application #
2176709
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1983-12-01
Project End
1998-04-14
Budget Start
1996-07-01
Budget End
1998-04-14
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Biochemistry
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Tarafdar, Pradip K; Chakraborty, Hirak; Bruno, Michael J et al. (2015) Phosphatidylserine-Dependent Catalysis of Stalk and Pore Formation by Synaptobrevin JMR-TMD Peptide. Biophys J 109:1863-72
Sengupta, Tanusree; Chakraborty, Hirak; Lentz, Barry R (2014) The transmembrane domain peptide of vesicular stomatitis virus promotes both intermediate and pore formation during PEG-mediated vesicle fusion. Biophys J 107:1318-26
Chakraborty, Hirak; Sengupta, Tanusree; Lentz, Barry R (2014) pH Alters PEG-mediated fusion of phosphatidylethanolamine-containing vesicles. Biophys J 107:1327-38
Majumder, Rinku; Koklic, Tilen; Rezaie, Alireza R et al. (2013) Phosphatidylserine-induced factor Xa dimerization and binding to factor Va are competing processes in solution. Biochemistry 52:143-51
Chakraborty, Hirak; Tarafdar, Pradip K; Klapper, David G et al. (2013) Wild-type and mutant hemagglutinin fusion peptides alter bilayer structure as well as kinetics and activation thermodynamics of stalk and pore formation differently: mechanistic implications. Biophys J 105:2495-506
Tenchov, Boris G; MacDonald, Robert C; Lentz, Barry R (2013) Fusion peptides promote formation of bilayer cubic phases in lipid dispersions. An x-ray diffraction study. Biophys J 104:1029-37
Chakraborty, Hirak; Tarafdar, Pradip K; Lentz, Barry R (2013) A novel assay for detecting fusion pore formation: implications for the fusion mechanism. Biochemistry 52:8510-7
Tarafdar, Pradip K; Chakraborty, Hirak; Dennison, S Moses et al. (2012) Phosphatidylserine inhibits and calcium promotes model membrane fusion. Biophys J 103:1880-9
Chakraborty, Hirak; Lentz, Barry R (2012) A simple method for correction of circular dichroism spectra obtained from membrane-containing samples. Biochemistry 51:1005-8
Majumder, Rinku; Liang, Xiaoe; Quinn-Allen, Mary Ann et al. (2011) Modulation of prothrombinase assembly and activity by phosphatidylethanolamine. J Biol Chem 286:35535-42

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