Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM033589-11A1
Application #
2177068
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1983-12-01
Project End
1999-11-30
Budget Start
1995-12-11
Budget End
1996-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Chicago
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Vorogushin, Andrei V; Wulff, William D; Hansen, Hans-Jurgen (2008) Central-to-Axial Chirality Transfer in the Benzannulation Reaction of Optically Pure Fischer Carbene Complexes in the Synthesis of Allocolchicinoids. Tetrahedron 64:949-968
Korthals, Keith A; Wulff, William D (2008) Traceless stereoinduction in the one-pot assembly of all three rings of hexahydrodibenzopyrans. J Am Chem Soc 130:2898-9
Huang, Jie; Wang, Huan; Wu, Chunrui et al. (2007) Intramolecular cyclohexadienone annulations of Fischer carbene complexes: model studies for the synthesis of Phomactins. Org Lett 9:2799-802
Huang, Jie; Wu, Chunrui; Wulff, William D (2007) Total synthesis of (+/-)-phomactin B2 via an intramolecular cyclohexadienone annulation of a chromium carbene complex. J Am Chem Soc 129:13366-7
Rawat, Manish; Prutyanov, Victor; Wulff, William D (2006) Chromene chromium carbene complexes in the syntheses of naphthopyran and naphthopyrandione units present in photochromic materials and biologically active natural products. J Am Chem Soc 128:11044-53
Lian, Yiqian; Wulff, William D (2005) Iron in the service of chromium: the ortho-benzannulation of trans,trans-dienyl Fischer carbene complexes. J Am Chem Soc 127:17162-3
Jiang, May Xiao-Wu; Rawat, Manish; Wulff, William D (2004) Contingency and serendipity in the reactions of Fischer carbene complexes with conjugated triynes. J Am Chem Soc 126:5970-1
Rawat, Manish; Wulff, William D (2004) Total synthesis of carbazoquinocin C: application of the o-benzannulation of Fischer carbene complexes to carbazole-3,4-quinone alkaloids. Org Lett 6:329-32
Vorogushin, Andrei V; Wulff, William D; Hansen, Hans-Jurgen (2003) Steric vs hydrogen-bonding control of atropisomerization: preparation of either diastereomer of configurationally stable allocolchicinoids. J Org Chem 68:9618-23
Vorogushin, Andrei V; Predeus, Alexander V; Wulff, William D et al. (2003) Diels-Alder reaction-aromatization approach toward functionalized ring C allocolchicinoids. Enantioselective total synthesis of (-)-7S-allocolchicine. J Org Chem 68:5826-31

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