Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM034262-03S1
Application #
3284935
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1985-01-01
Project End
1988-03-31
Budget Start
1988-01-01
Budget End
1988-03-31
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Iowa State University
Department
Type
Earth Sciences/Resources
DUNS #
City
Ames
State
IA
Country
United States
Zip Code
50011
Huang, H Y; Graves, D J; Robson, R M et al. (1993) ADP-ribosylation of the intermediate filament protein desmin and inhibition of desmin assembly in vitro by muscle ADP-ribosyltransferase. Biochem Biophys Res Commun 197:570-7
Kharadia, S V; Huiatt, T W; Huang, H Y et al. (1992) Effect of an arginine-specific ADP-ribosyltransferase inhibitor on differentiation of embryonic chick skeletal muscle cells in culture. Exp Cell Res 201:33-42
Larew, J S; Peterson, J E; Graves, D J (1991) Determination of the kinetic mechanism of arginine-specific ADP-ribosyltransferases using a high performance liquid chromatographic assay. J Biol Chem 266:52-7
Peterson, J E; Larew, J S; Graves, D J (1990) Purification and partial characterization of arginine-specific ADP-ribosyltransferase from skeletal muscle microsomal membranes. J Biol Chem 265:17062-9
Kim, E S; Graves, D J (1990) Development of a high-performance liquid chromatography assay method and characterization of adenosine diphosphate-ribosylarginine hydrolase in skeletal muscle. Anal Biochem 187:251-7
Narayanan, J; Hartman, P A; Graves, D J (1989) Assay of heat-labile enterotoxins by their ADP-ribosyltransferase activities. J Clin Microbiol 27:2414-9
Soman, G; Graves, D J (1988) Endogenous ADP-ribosylation in skeletal muscle membranes. Arch Biochem Biophys 260:56-66
Kharadia, S V; Graves, D J (1987) Relationship of phosphorylation and ADP-ribosylation using a synthetic peptide as a model substrate. J Biol Chem 262:17379-83
Chang, Y C; Soman, G; Graves, D J (1986) Identification of an enzymatic activity that hydrolyzes protein-bound ADP-ribose in skeletal muscle. Biochem Biophys Res Commun 139:932-9
Chang, Y C; Scott, R D; Graves, D J (1986) Function of pyridoxal 5'-phosphate in glycogen phosphorylase: 19F NMR and kinetic studies of phosphorylase reconstituted with 6-fluoropyridoxal and 6-fluoropyridoxal phosphate. Biochemistry 25:1932-9

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