The Fidelity of IN Vitro DNA Repair and Replication

Masker, Warren E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM034614-10
• Application #: 2177512
• Study Section: Microbial Physiology and Genetics Subcommittee 2 (MBC)
• Project Start: 1984-08-01
• Project End: 1997-03-31
• Budget Start: 1993-04-01
• Budget End: 1997-03-31
• Support Year: 10
• Fiscal Year: 1993

Institution

• Name: Temple University
• Department: Biochemistry
• Type: Schools of Medicine
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19122

Publications

Yang, Y; Masker, W (1997) Double-strand breaks increase the incidence of genetic deletion associated with intermolecular recombination in bacteriophage T7. Mol Gen Genet 255:277-84

Yang, Y; Masker, W (1996) Instability of repeated dinucleotides in bacteriophage T7 genomes. Mutat Res 354:113-27

Yang, Y; Masker, W (1996) Deletion during recombination in bacteriophage T7. Mutat Res 349:21-32

Kong, D; Masker, W (1994) Deletion between direct repeats in T7 DNA stimulated by double-strand breaks. J Bacteriol 176:5904-11

Kong, D; Masker, W (1993) Deletion between directly repeated DNA sequences measured in extracts of bacteriophage T7-infected Escherichia coli. J Biol Chem 268:7721-7

Masker, W; Crissey, M A (1993) The effect of the 3'-->5' exonuclease of T7 DNA polymerase on frameshifts and deletions. Mutat Res 301:235-41

Scearce, L M; Masker, W (1993) Deletion between direct repeats in bacteriophage T7 gene 1.2. Mutat Res 288:301-10

Pierce, J C; Masker, W (1992) Frameshift mutagenesis in bacteriophage T7. Mutat Res 281:81-7

Masker, W (1992) In vitro repair of double-strand breaks accompanied by recombination in bacteriophage T7 DNA. J Bacteriol 174:155-60

Scearce, L M; Pierce, J C; McInroy, B et al. (1991) Deletion mutagenesis independent of recombination in bacteriophage T7. J Bacteriol 173:869-78