Phosphate Regulation of Genes in Escherichia coli

Wanner, Barry L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM035392-09
• Application #: 2177874
• Study Section: Microbial Physiology and Genetics Subcommittee 2 (MBC)
• Project Start: 1985-01-01
• Project End: 1996-11-30
• Budget Start: 1994-12-01
• Budget End: 1996-11-30
• Support Year: 9
• Fiscal Year: 1995

Institution

• Name: Purdue University
• Department: Biology
• Type: Schools of Arts and Sciences
• DUNS #: 072051394
• City: West Lafayette
• State: IN
• Country: United States
• Zip Code: 47907

Publications

Baker, A S; Ciocci, M J; Metcalf, W W et al. (1998) Insights into the mechanism of catalysis by the P-C bond-cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis. Biochemistry 37:9305-15

Haldimann, A; Fisher, S L; Daniels, L L et al. (1997) Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12. J Bacteriol 179:5903-13

Wanner, B L (1996) Signal transduction in the control of phosphate-regulated genes of Escherichia coli. Kidney Int 49:964-7

Metcalf, W W; Jiang, W; Daniels, L L et al. (1996) Conditionally replicative and conjugative plasmids carrying lacZ alpha for cloning, mutagenesis, and allele replacement in bacteria. Plasmid 35:1-13

Fisher, S L; Kim, S K; Wanner, B L et al. (1996) Kinetic comparison of the specificity of the vancomycin resistance VanSfor two response regulators, VanR and PhoB. Biochemistry 35:4732-40

Haldimann, A; Prahalad, M K; Fisher, S L et al. (1996) Altered recognition mutants of the response regulator PhoB: a new genetic strategy for studying protein-protein interactions. Proc Natl Acad Sci U S A 93:14361-6

Jiang, W; Metcalf, W W; Lee, K S et al. (1995) Molecular cloning, mapping, and regulation of Pho regulon genes for phosphonate breakdown by the phosphonatase pathway of Salmonella typhimurium LT2. J Bacteriol 177:6411-21

Fisher, S L; Jiang, W; Wanner, B L et al. (1995) Cross-talk between the histidine protein kinase VanS and the response regulator PhoB. Characterization and identification of a VanS domain that inhibits activation of PhoB. J Biol Chem 270:23143-9

Wanner, B L (1994) Molecular genetics of carbon-phosphorus bond cleavage in bacteria. Biodegradation 5:175-84

Metcalf, W W; Wanner, B L (1993) Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements. J Bacteriol 175:3430-42