Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM035751-10
Application #
2178052
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1986-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Ehretsmann, C P; Chandler, L A; Bourgeois, S (1995) A nuclear post-transcriptional mechanism mediates the induction of fibronectin by glucocorticoids. Mol Cell Endocrinol 110:185-94
Chandler, L A; Ehretsmann, C P; Bourgeois, S (1994) A novel mechanism of Ha-ras oncogene action: regulation of fibronectin mRNA levels by a nuclear posttranscriptional event. Mol Cell Biol 14:3085-93
Bowlus, C L; McQuillan, J J; Dean, D C (1991) Characterization of three different elements in the 5'-flanking region of the fibronectin gene which mediate a transcriptional response to cAMP. J Biol Chem 266:1122-7
Chandler, L A; Bourgeois, S (1991) Posttranscriptional down-regulation of fibronectin in N-ras-transformed cells. Cell Growth Differ 2:379-84
Dean, D C; McQuillan, J J; Weintraub, S (1990) Serum stimulation of fibronectin gene expression appears to result from rapid serum-induced binding of nuclear proteins to a cAMP response element. J Biol Chem 265:3522-7
Dean, D C; Blakeley, M S; Newby, R F et al. (1989) Forskolin inducibility and tissue-specific expression of the fibronectin promoter. Mol Cell Biol 9:1498-506
Dean, D C; Newby, R F; Bourgeois, S (1988) Regulation of fibronectin biosynthesis by dexamethasone, transforming growth factor beta, and cAMP in human cell lines. J Cell Biol 106:2159-70
Dean, D C; Bowlus, C L; Bourgeois, S (1987) Cloning and analysis of the promotor region of the human fibronectin gene. Proc Natl Acad Sci U S A 84:1876-80