Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036516-11
Application #
2178403
Study Section
Biochemistry Study Section (BIO)
Project Start
1986-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Nayak, Sunil; Bryant, Floyd R (2015) Kinetics of the ATP and dATP-mediated formation of a functionally-active RecA-ssDNA complex. Biochem Biophys Res Commun 463:1257-61
Grove, Diane E; Anne, Geetha; Hedayati, Mohammad A et al. (2012) Stimulation of the Streptococcus pneumoniae RecA protein-promoted three-strand exchange reaction by the competence-specific SsbB protein. Biochem Biophys Res Commun 424:40-4
Steffen, Scott E; Bryant, Floyd R (2012) Altered nucleotide cofactor-dependent properties of the mutant [S240K]RecA protein. Biochem Biophys Res Commun 421:527-31
Katz, Francine S; Bryant, Floyd R (2003) Three-strand exchange by the Escherichia coli RecA protein using ITP as a nucleotide cofactor: mechanistic parallels with the ATP-dependent reaction of the RecA protein from Streptococcus pneumoniae. J Biol Chem 278:35889-96
Steffen, Scott E; Katz, Francine S; Bryant, Floyd R (2002) Complete inhibition of Streptococcus pneumoniae RecA protein-catalyzed ATP hydrolysis by single-stranded DNA-binding protein (SSB protein): implications for the mechanism of SSB protein-stimulated DNA strand exchange. J Biol Chem 277:14493-500
Hedayati, Mohammad A; Steffen, Scott E; Bryant, Floyd R (2002) Effect of the Streptococcus pneumoniae MmsA protein on the RecA protein-promoted three-strand exchange reaction. Implications for the mechanism of transformational recombination. J Biol Chem 277:24863-9
Katz, F S; Bryant, F R (2001) Interdependence of the kinetics of NTP hydrolysis and the stability of the RecA-ssDNA complex. Biochemistry 40:11082-9
Steffen, S E; Bryant, F R (2001) Purification and characterization of the single-stranded DNA binding protein from Streptococcus pneumoniae. Arch Biochem Biophys 388:165-70
Nayak, S; Hildebrand, E L; Bryant, F R (2001) ADP-dependent DNA strand exchange by the mutant [P67G/E68A] RecA protein. J Biol Chem 276:14933-8
Steffen, S E; Bryant, F R (2000) Purification and characterization of the RecA protein from Streptococcus pneumoniae. Arch Biochem Biophys 382:303-9

Showing the most recent 10 out of 28 publications