Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM036604-02
Application #
3290916
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1986-04-01
Project End
1987-07-31
Budget Start
1987-04-01
Budget End
1987-07-31
Support Year
2
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Werneburg, B G; Ash, D E (1997) VO2+(IV) complexes with pyruvate carboxylase: activation of oxaloacetate decarboxylation and EPR properties of enzyme-VO2+ complexes. Biochemistry 36:14392-402
Reczkowski, R S; Ash, D E (1994) Rat liver arginase: kinetic mechanism, alternate substrates, and inhibitors. Arch Biochem Biophys 312:31-7
Werneburg, B G; Ash, D E (1993) Chemical modifications of chicken liver pyruvate carboxylase: evidence for essential cysteine-lysine pairs and a reactive sulfhydryl group. Arch Biochem Biophys 303:214-21
Kanyo, Z F; Chen, C Y; Daghigh, F et al. (1992) Crystallization and oligomeric structure of rat liver arginase. J Mol Biol 224:1175-7
Chen, C Y; Sato, Y; Schramm, V L (1991) Isotope trapping and positional isotope exchange with rat and chicken liver phosphoenolpyruvate carboxykinases. Biochemistry 30:4143-51
Chen, C Y; Emig, F A; Schramm, V L et al. (1991) Inactivation of chicken mitochondrial phosphoenolpyruvate carboxykinase by o-phthalaldehyde. J Biol Chem 266:16645-52
Wente, S R; Villalba, M; Schramm, V L et al. (1990) Mn2(+)-binding properties of a recombinant protein-tyrosine kinase derived from the human insulin receptor. Proc Natl Acad Sci U S A 87:2805-9
Merkler, D J; Brenowitz, M; Schramm, V L (1990) The rate constant describing slow-onset inhibition of yeast AMP deaminase by coformycin analogues is independent of inhibitor structure. Biochemistry 29:8358-64
Merkler, D J; Schramm, V L (1990) Catalytic and regulatory site composition of yeast AMP deaminase by comparative binding and rate studies. Resolution of the cooperative mechanism. J Biol Chem 265:4420-6
Ash, D E; Emig, F A; Chowdhury, S A et al. (1990) Mammalian and avian liver phosphoenolpyruvate carboxykinase. Alternate substrates and inhibition by analogues of oxaloacetate. J Biol Chem 265:7377-84

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