Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM037823-04
Application #
3293598
Study Section
Molecular Biology Study Section (MBY)
Project Start
1986-04-01
Project End
1990-06-30
Budget Start
1990-04-01
Budget End
1990-06-30
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Synergen, Inc.
Department
Type
DUNS #
City
Boulder
State
CO
Country
United States
Zip Code
80301
Xie, H; Hirsh, D (1998) In vivo function of mutated spliced leader RNAs in Caenorhabditis elegans. Proc Natl Acad Sci U S A 95:4235-40
Greenbaum, N L; Radhakrishnan, I; Hirsh, D et al. (1995) Determination of the folding topology of the SL1 RNA from Caenorhabditis elegans by multidimensional heteronuclear NMR. J Mol Biol 252:314-27
Saotome, Y; Winter, C G; Hirsh, D (1995) A widely expressed novel C2H2 zinc-finger protein with multiple consensus phosphorylation sites is conserved in mouse and man. Gene 152:233-8
Li, S C; Rothman, P B; Zhang, J et al. (1994) Expression of I mu-C gamma hybrid germline transcripts subsequent to immunoglobulin heavy chain class switching. Int Immunol 6:491-7
Huang, X Y; Hirsh, D (1992) RNA trans-splicing. Genet Eng (N Y) 14:211-29
Lee, Y H; Huang, X Y; Hirsh, D et al. (1992) Conservation of gene organization and trans-splicing in the glyceraldehyde-3-phosphate dehydrogenase-encoding genes of Caenorhabditis briggsae. Gene 121:227-35
Huang, X Y; Hirsh, D (1989) A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A 86:8640-4
Krause, M; Wild, M; Rosenzweig, B et al. (1989) Wild-type and mutant actin genes in Caenorhabditis elegans. J Mol Biol 208:381-92
Bektesh, S L; Hirsh, D I (1988) C. elegans mRNAs acquire a spliced leader through a trans-splicing mechanism. Nucleic Acids Res 16:5692
Bektesh, S; Van Doren, K; Hirsh, D (1988) Presence of the Caenorhabditis elegans spliced leader on different mRNAs and in different genera of nematodes. Genes Dev 2:1277-83

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