Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM038433-10
Application #
2179330
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1985-09-01
Project End
1996-11-30
Budget Start
1994-12-01
Budget End
1996-11-30
Support Year
10
Fiscal Year
1995
Total Cost
Indirect Cost
Name
West Virginia University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506
Wang, Y; Bruel, C; Yan, L et al. (1998) Exogenous ubiquinol analogues affect the fluorescence of NCD-4 bound to aspartate-160 of yeast cytochrome b. J Bioenerg Biomembr 30:455-64
Obungu, V H; Wang, Y; Beattie, D S (1998) The role of charged amino acids in the alpha1-beta4 loop of the iron-sulfur protein of the cytochrome bc1 complex of yeast mitochondria. J Biol Chem 273:11917-22
Wang, Y; Obungu, V; Beattie, D S (1998) Dicyclohexylcarbodiimide inhibits proton pumping in ubiquinol:cytochrome c oxidoreductase of Rhodobacter sphaeroides and binds to aspartate-187 of cytochrome b. Arch Biochem Biophys 352:193-8
Ramabadran, R S; Japa, S; Beattie, D S (1997) Assembly of deletion mutants of the Rieske iron-sulfur protein into the cytochrome bc1 complex of yeast mitochondria. J Bioenerg Biomembr 29:45-54
Obungu, V; Yu, L P; Japa, S et al. (1997) The role of the membrane-spanning and extra-membranous regions of the iron-sulfur protein in its assembly into the cytochrome bc1 complex of yeast mitochondria. Biochim Biophys Acta 1321:229-37
Beattie, D S; Howton, M M (1996) The presence of rotenone-sensitive NADH dehydrogenase in the long slender bloodstream and the procyclic forms of Trypanosoma brucei brucei. Eur J Biochem 241:888-94
Wang, Y; Howton, M M; Beattie, D S (1995) Topographical organization of cytochrome b in the yeast mitochondrial membrane determined by fluorescence studies with N-cyclohexyl-N'-[4-(dimethylamino)naphthyl]carbodiimide. Biochemistry 34:7476-82
Japa, S; Sun, J Z; Beattie, D S (1995) Import of subunit VII of the cytochrome bc1 complex into yeast mitochondrial. Arch Biochem Biophys 319:250-6
Japa, S; Beattie, D S (1994) Sequences of the iron-sulfur protein precursor necessary for its import and two-step processing in yeast mitochondria. Arch Biochem Biophys 312:414-20
Beattie, D S; Obungu, V H; Kiaira, J K (1994) Oxidation of NADH by a rotenone and antimycin-sensitive pathway in the mitochondrion of procyclic Trypanosoma brucei brucei. Mol Biochem Parasitol 64:87-94

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