Protein Engineering-Peptide Hormone Design

Taylor, John W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 2R01GM038811-03
• Application #: 3295513
• Study Section: Physical Biochemistry Study Section (PB)
• Project Start: 1988-04-01
• Project End: 1991-08-31
• Budget Start: 1991-06-01
• Budget End: 1991-08-31
• Support Year: 3
• Fiscal Year: 1991

Institution

• Name: Rockefeller University
• Type: Other Domestic Higher Education
• DUNS #: 071037113
• City: New York
• State: NY
• Country: United States
• Zip Code: 10065

Publications

Kapurniotu, A; Taylor, J W (1995) Structural and conformational requirements for human calcitonin activity: design, synthesis, and study of lactam-bridged analogues. J Med Chem 38:836-47

Taylor, J W; Shih, I L; Lees, A M et al. (1993) Surface-induced conformational switching in amphiphilic peptide segments of apolipoproteins B and E and model peptides. Int J Pept Protein Res 41:536-47

Bouvier, M; Taylor, J W (1992) Probing the functional conformation of neuropeptide Y through the design and study of cyclic analogues. J Med Chem 35:1145-55