Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM038836-07
Application #
2179567
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1988-09-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Kentucky
Department
Pharmacology
Type
Schools of Medicine
DUNS #
832127323
City
Lexington
State
KY
Country
United States
Zip Code
40506
Oo, C Y; Paxton, E W; McNamara, P J (2001) Active transport of nitrofurantoin into rat milk. Adv Exp Med Biol 501:547-52
Gerk, P M; Oo, C Y; Paxton, E W et al. (2001) Interactions between cimetidine, nitrofurantoin, and probenecid active transport into rat milk. J Pharmacol Exp Ther 296:175-80
Gerk, P M; Paxton, E W; Bandyopadhyay, A M et al. (2001) Influence of lysine on cimetidine uptake and on excretion of cimetidine by the rat mammary gland. Adv Exp Med Biol 501:553-8
McNamara, P J; Meece, J A; Paxton, E (1996) Active transport of cimetidine and ranitidine into the milk of Sprague Dawley rats. J Pharmacol Exp Ther 277:1615-21
Oo, C Y; Kuhn, R J; Desai, N et al. (1995) Pharmacokinetics in lactating women: prediction of alprazolam transfer into milk. Br J Clin Pharmacol 40:231-6
Oo, C Y; Burgio, D E; Kuhn, R C et al. (1995) Pharmacokinetics of caffeine and its demethylated metabolites in lactation: predictions of milk to serum concentration ratios. Pharm Res 12:313-6
Oo, C Y; Kuhn, R J; Desai, N et al. (1995) Active transport of cimetidine into human milk. Clin Pharmacol Ther 58:548-55
Yoo, S D; Burgio, D E; McNamara, P J (1994) Phenobarbital disposition in adult and neonatal rabbits. Pharm Res 11:1204-6
McNamara, P J; Burgio, D; Yoo, S D (1992) Pharmacokinetics of cimetidine during lactation: species differences in cimetidine transport into rat and rabbit milk. J Pharmacol Exp Ther 261:918-23
McNamara, P J; Burgio, D; Yoo, S D (1992) Pharmacokinetics of caffeine and its demethylated metabolites in lactating adult rabbits and neonatal offspring. Predictions of breast milk to serum concentration ratios. Drug Metab Dispos 20:302-8

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