Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM039693-08
Application #
2179966
Study Section
Special Emphasis Panel (ZRG7-SSS-2 (14))
Project Start
1988-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
De Wulf, P; Lin, E C (2000) Cpx two-component signal transduction in Escherichia coli: excessive CpxR-P levels underlie CpxA* phenotypes. J Bacteriol 182:1423-6
Pellicer, M T; Fernandez, C; Badia, J et al. (1999) Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter. J Biol Chem 274:1745-52
Membrillo-Hernandez, J; Lin, E C (1999) Regulation of expression of the adhE gene, encoding ethanol oxidoreductase in Escherichia coli: transcription from a downstream promoter and regulation by fnr and RpoS. J Bacteriol 181:7571-9
De Wulf, P; Kwon, O; Lin, E C (1999) The CpxRA signal transduction system of Escherichia coli: growth-related autoactivation and control of unanticipated target operons. J Bacteriol 181:6772-8
McGuire, A M; De Wulf, P; Church, G M et al. (1999) A weight matrix for binding recognition by the redox-response regulator ArcA-P of Escherichia coli. Mol Microbiol 32:219-21
Pogliano, J; Lynch, A S; Belin, D et al. (1997) Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system. Genes Dev 11:1169-82
Aristarkhov, A; Mikulskis, A; Belasco, J G et al. (1996) Translation of the adhE transcript to produce ethanol dehydrogenase requires RNase III cleavage in Escherichia coli. J Bacteriol 178:4327-32
Lynch, A S; Lin, E C (1996) Transcriptional control mediated by the ArcA two-component response regulator protein of Escherichia coli: characterization of DNA binding at target promoters. J Bacteriol 178:6238-49
Chen, Y M; Lin, E C (1991) Regulation of the adhE gene, which encodes ethanol dehydrogenase in Escherichia coli. J Bacteriol 173:8009-13
Hidalgo, E; Chen, Y M; Lin, E C et al. (1991) Molecular cloning and DNA sequencing of the Escherichia coli K-12 ald gene encoding aldehyde dehydrogenase. J Bacteriol 173:6118-23

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