Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM040540-04
Application #
2180417
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1992-02-01
Project End
1997-03-31
Budget Start
1995-02-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Georgia Institute of Technology
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
097394084
City
Atlanta
State
GA
Country
United States
Zip Code
30332

  Publications

Wang, Hui; Mao, Shu; Chalovich, Joseph M et al. (2008) Tropomyosin dynamics in cardiac thin filaments: a multisite forster resonance energy transfer and anisotropy study. Biophys J 94:4358-69
Bauer, John D; Sunman, Jeffrey A; Foster, Michael S et al. (2007) Anti-inflammatory effects of 4-phenyl-3-butenoic acid and 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester, potential inhibitors of neuropeptide bioactivation. J Pharmacol Exp Ther 320:1171-7
Sunman, Jeffrey A; Foster, Michael S; Folse, Stacey L et al. (2004) Reversal of the transformed phenotype and inhibition of peptidylglycine alpha-monooxygenase in Ras-transformed cells by 4-phenyl-3-butenoic acid. Mol Carcinog 41:231-46
McIninch, Jane K; McIninch, James D; May, Sheldon W (2003) Catalysis, stereochemistry, and inhibition of ureidoglycolate lyase. J Biol Chem 278:50091-100
Feng, J; May, S W (2001) High-performance liquid chromatographic enantiomeric separation of an enzyme inhibitor which possesses both a chiral center and tautomeric moieties. J Chromatogr A 905:103-9
Abou-Mohamed, G A; Huang, J; Oldham, C D et al. (2000) Vascular and endothelial actions of inhibitors of substance P amidation. J Cardiovasc Pharmacol 35:871-80
Kaesemeyer, W H; Ogonowski, A A; Jin, L et al. (2000) Endothelial nitric oxide synthase is a site of superoxide synthesis in endothelial cells treated with glyceryl trinitrate. Br J Pharmacol 131:1019-23
Feng, J; Shi, J; Sirimanne, S R et al. (2000) Kinetic and stereochemical studies on novel inactivators of C-terminal amidation. Biochem J 350 Pt 2:521-30
Moore, A B; May, S W (1999) Kinetic and inhibition studies on substrate channelling in the bifunctional enzyme catalysing C-terminal amidation. Biochem J 341 ( Pt 1):33-40
Cutler, S J; DeWitt Blanton Jr, C; Akin, D T et al. (1998) Pharmacological evaluation of 1-(carboxymethyl)-3,5-diphenyl-2-methylbenzene, a novel arylacetic acid with potential anti-inflammatory properties. Inflamm Res 47:316-24

Showing the most recent 10 out of 16 publications