Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM041026-01
Application #
3299028
Study Section
Biochemistry Study Section (BIO)
Project Start
1988-12-01
Project End
1992-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
1
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Bernstrom, K; Kayganich, K; Murphy, R C et al. (1992) Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids. J Biol Chem 267:3686-90
Zahniser, N R; Cass, W A; Fitzpatrick, F A (1992) Signal transduction pathways involved in presynaptic receptor-mediated inhibition of dopamine release in rat striatum. Neurochem Int 20 Suppl:85S-88S
Malcolm, K C; Fitzpatrick, F A (1992) Indirect actions of thapsigargin on human platelets: activation of eicosanoid biosynthesis and cellular signaling pathways. J Pharmacol Exp Ther 260:1244-9
Malcolm, K C; Fitzpatrick, F A (1992) Epoxyeicosatrienoic acids inhibit Ca2+ entry into platelets stimulated by thapsigargin and thrombin. J Biol Chem 267:19854-8
Hill, E; Fitzpatrick, F; Murphy, R C (1992) Biological activity and metabolism of 20-hydroxyeicosatetraenoic acid in the human platelet. Br J Pharmacol 106:267-74
Bernstrom, K; Malcolm, K; McGee, J et al. (1991) 14, 15-cis-episulfide-eicosatrienoic acid, an 'epoxygenase' eicosanoid analog, inhibits ionophore- but not thrombin-induced platelet aggregation. Mol Pharmacol 39:114-9
Cass, W A; Larson, G; Fitzpatrick, F A et al. (1991) Inhibitors of arachidonic acid metabolism: effects on rat striatal dopamine release and uptake. J Pharmacol Exp Ther 257:990-6
Carroll, M A; Sala, A; Dunn, C E et al. (1991) Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells. J Biol Chem 266:12306-12
Bernstrom, K; Kayganich, K; Murphy, R C (1991) Collisionally induced dissociation of epoxyeicosatrienoic acids and epoxyeicosatrienoic acid-phospholipid molecular species. Anal Biochem 198:203-11
Jones, D A; Fitzpatrick, F A; Malcolm, K C (1991) Thromboxane A2 synthesis in human erythroleukemia cells. Biochem Biophys Res Commun 180:8-14

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