Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM041752-08
Application #
2181037
Study Section
Molecular Biology Study Section (MBY)
Project Start
1989-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111

  Publications

Graber, Joel H; Nazeer, Fathima I; Yeh, Pei-chun et al. (2013) DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast. Genome Res 23:1690-703
Ezeokonkwo, Chukwudi; Ghazy, Mohamed A; Zhelkovsky, Alexander et al. (2012) Novel interactions at the essential N-terminus of poly(A) polymerase that could regulate poly(A) addition in Saccharomyces cerevisiae. FEBS Lett 586:1173-8
Schmid, Manfred; Poulsen, Mathias Bach; Olszewski, Pawel et al. (2012) Rrp6p controls mRNA poly(A) tail length and its decoration with poly(A) binding proteins. Mol Cell 47:267-80
Gordon, James M B; Shikov, Sergei; Kuehner, Jason N et al. (2011) Reconstitution of CF IA from overexpressed subunits reveals stoichiometry and provides insights into molecular topology. Biochemistry 50:10203-14
Kuehner, Jason N; Pearson, Erika L; Moore, Claire (2011) Unravelling the means to an end: RNA polymerase II transcription termination. Nat Rev Mol Cell Biol 12:283-94
Ezeokonkwo, Chukwudi; Zhelkovsky, Alexander; Lee, Rosanna et al. (2011) A flexible linker region in Fip1 is needed for efficient mRNA polyadenylation. RNA 17:652-64
Zhao, J; Kessler, M; Helmling, S et al. (1999) Pta1, a component of yeast CF II, is required for both cleavage and poly(A) addition of mRNA precursor. Mol Cell Biol 19:7733-40
Aranda, A; Perez-Ortin, J E; Moore, C et al. (1998) Transcription termination downstream of the Saccharomyces cerevisiae FBP1 [changed from FPB1] poly(A) site does not depend on efficient 3'end processing. RNA 4:303-18
Zhao, J; Kessler, M M; Moore, C L (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272:10831-8
Kessler, M M; Henry, M F; Shen, E et al. (1997) Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast. Genes Dev 11:2545-56

Showing the most recent 10 out of 12 publications