Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM043238-05
Application #
2181902
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1991-08-01
Project End
1997-06-30
Budget Start
1995-08-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Graf, Paul C F; Martinez-Yamout, Maria; VanHaerents, Stephen et al. (2004) Activation of the redox-regulated chaperone Hsp33 by domain unfolding. J Biol Chem 279:20529-38
Xia, Bin; Tsui, Vickie; Case, David A et al. (2002) Comparison of protein solution structures refined by molecular dynamics simulation in vacuum, with a generalized Born model, and with explicit water. J Biomol NMR 22:317-31
Xia, B; Vlamis-Gardikas, A; Holmgren, A et al. (2001) Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases. J Mol Biol 310:907-18
Duggan, B M; Legge, G B; Dyson, H J et al. (2001) SANE (Structure Assisted NOE Evaluation): an automated model-based approach for NOE assignment. J Biomol NMR 19:321-9
Xia, B; Chung, J; Vlamis-Gardikas, A et al. (1999) Assignment of 1H, 13C, and 15N resonances of reduced Escherichia coli glutaredoxin 2. J Biomol NMR 14:197-8
Jeng, M F; Reymond, M T; Tennant, L L et al. (1998) NMR characterization of a single-cysteine mutant of Escherichia coli thioredoxin and a covalent thioredoxin-peptide complex. Eur J Biochem 257:299-308
Dillet, V; Dyson, H J; Bashford, D (1998) Calculations of electrostatic interactions and pKas in the active site of Escherichia coli thioredoxin. Biochemistry 37:10298-306
Zhu, L; Dyson, H J; Wright, P E (1998) A NOESY-HSQC simulation program, SPIRIT. J Biomol NMR 11:17-29
Dyson, H J; Jeng, M F; Tennant, L L et al. (1997) Effects of buried charged groups on cysteine thiol ionization and reactivity in Escherichia coli thioredoxin: structural and functional characterization of mutants of Asp 26 and Lys 57. Biochemistry 36:2622-36
Slaby, I; Cerna, V; Jeng, M F et al. (1996) Replacement of Trp28 in Escherichia coli thioredoxin by site-directed mutagenesis affects thermodynamic stability but not function. J Biol Chem 271:3091-6

Showing the most recent 10 out of 19 publications