Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM045434-06
Application #
2183167
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1991-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Physiology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Lefer, A M; Weyrich, A S; Buerke, M (1994) Role of selectins, a new family of adhesion molecules, in ischaemia-reperfusion injury. Cardiovasc Res 28:289-94
Albertine, K H; Weyrich, A S; Ma, X L et al. (1994) Quantification of neutrophil migration following myocardial ischemia and reperfusion in cats and dogs. J Leukoc Biol 55:557-66
Murohara, T; Buerke, M; Lefer, A M (1994) Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins. Arterioscler Thromb 14:1509-19
Lefer, A M; Ma, X L (1994) PMN adherence to cat ischemic-reperfused mesenteric vascular endothelium under flow: role of P-selectin. J Appl Physiol 76:33-8
Mead, P S; Guo, J P; Lefer, A M et al. (1994) Protective effects of a monoclonal antibody against lipid A in endotoxic shock. Methods Find Exp Clin Pharmacol 16:405-12
Buerke, M; Weyrich, A S; Zheng, Z et al. (1994) Sialyl Lewisx-containing oligosaccharide attenuates myocardial reperfusion injury in cats. J Clin Invest 93:1140-8
Gauthier, T W; Davenpeck, K L; Lefer, A M (1994) Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion. Am J Physiol 267:G562-8
Lefer, A M; Murohara, T; Buerke, M (1994) Effects of taprostene on neutrophil-endothelial interactions in isolated coronary arteries. Methods Find Exp Clin Pharmacol 16:623-31
Buerke, M; Weyrich, A S; Murohara, T et al. (1994) Humanized monoclonal antibody DREG-200 directed against I-selectin protects in feline myocardial reperfusion injury. J Pharmacol Exp Ther 271:134-42
Weyrich, A S; Ma, X L; Buerke, M et al. (1994) Physiological concentrations of nitric oxide do not elicit an acute negative inotropic effect in unstimulated cardiac muscle. Circ Res 75:692-700

Showing the most recent 10 out of 24 publications