Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM045441-06
Application #
2183173
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1991-01-01
Project End
1999-11-30
Budget Start
1995-12-05
Budget End
1996-11-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Genetics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Wang, Zhong; Willard, Huntington F; Mukherjee, Sayan et al. (2006) Evidence of influence of genomic DNA sequence on human X chromosome inactivation. PLoS Comput Biol 2:e113
Valley, Cory M; Pertz, Lisa M; Balakumaran, Bala S et al. (2006) Chromosome-wide, allele-specific analysis of the histone code on the human X chromosome. Hum Mol Genet 15:2335-47
Chadwick, Lisa Helbling; Pertz, Lisa M; Broman, Karl W et al. (2006) Genetic control of X chromosome inactivation in mice: definition of the Xce candidate interval. Genetics 173:2103-10
Amos-Landgraf, James M; Cottle, Amy; Plenge, Robert M et al. (2006) X chromosome-inactivation patterns of 1,005 phenotypically unaffected females. Am J Hum Genet 79:493-9
Chadwick, Lisa Helbling; Willard, Huntington F (2005) Genetic and parent-of-origin influences on X chromosome choice in Xce heterozygous mice. Mamm Genome 16:691-9
Chadwick, Brian P; Willard, Huntington F (2004) Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. Proc Natl Acad Sci U S A 101:17450-5
Chadwick, Brian P; Willard, Huntington F (2003) Barring gene expression after XIST: maintaining facultative heterochromatin on the inactive X. Semin Cell Dev Biol 14:359-67
Percec, Ivona; Thorvaldsen, Joanne L; Plenge, Robert M et al. (2003) An N-ethyl-N-nitrosourea mutagenesis screen for epigenetic mutations in the mouse. Genetics 164:1481-94
Chadwick, Brian P; Willard, Huntington F (2003) Chromatin of the Barr body: histone and non-histone proteins associated with or excluded from the inactive X chromosome. Hum Mol Genet 12:2167-78
Plenge, Robert M; Stevenson, Roger A; Lubs, Herbert A et al. (2002) Skewed X-chromosome inactivation is a common feature of X-linked mental retardation disorders. Am J Hum Genet 71:168-73

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