Thioredoxin and Cell Growth and Division

Muller, Eric G.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM045448-06
• Application #: 2183185
• Study Section: Microbial Physiology and Genetics Subcommittee 2 (MBC)
• Project Start: 1991-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 6
• Fiscal Year: 1996

Institution

• Name: University of Washington
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 135646524
• City: Seattle
• State: WA
• Country: United States
• Zip Code: 98195

Publications

Muller, E G (1996) A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth. Mol Biol Cell 7:1805-13

Muller, E G (1995) A redox-dependent function of thioredoxin is necessary to sustain a rapid rate of DNA synthesis in yeast. Arch Biochem Biophys 318:356-61

Steffen, B J; Butcher, E C; Engelhardt, B (1994) Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interaction with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. Am J Pathol 145:189-201

Muller, E G (1994) Deoxyribonucleotides are maintained at normal levels in a yeast thioredoxin mutant defective in DNA synthesis. J Biol Chem 269:24466-71

Muller, E G (1992) Thioredoxin genes in Saccharomyces cerevisiae: map positions of TRX1 and TRX2. Yeast 8:117-20

Muller, E G (1991) Thioredoxin deficiency in yeast prolongs S phase and shortens the G1 interval of the cell cycle. J Biol Chem 266:9194-202