Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM045768-04
Application #
2183390
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1992-09-30
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Rutgers University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901

  Publications

Martin, Charles E; Oh, Chan-Seok; Jiang, Yide (2007) Regulation of long chain unsaturated fatty acid synthesis in yeast. Biochim Biophys Acta 1771:271-85
Oh, Chan-Seok; Martin, Charles E (2006) Candida albicans Spt23p controls the expression of the Ole1p Delta9 fatty acid desaturase and regulates unsaturated fatty acid biosynthesis. J Biol Chem 281:7030-9
Kandasamy, Pitchaimani; Vemula, Muralikrishna; Oh, Chan-Seok et al. (2004) Regulation of unsaturated fatty acid biosynthesis in Saccharomyces: the endoplasmic reticulum membrane protein, Mga2p, a transcription activator of the OLE1 gene, regulates the stability of the OLE1 mRNA through exosome-mediated mechanisms. J Biol Chem 279:36586-92
Vemula, Muralikrishna; Kandasamy, Pitchaimani; Oh, Chan-Seok et al. (2003) Maintenance and regulation of mRNA stability of the Saccharomyces cerevisiae OLE1 gene requires multiple elements within the transcript that act through translation-independent mechanisms. J Biol Chem 278:45269-79
Jiang, Yide; Vasconcelles, Michael J; Wretzel, Sharon et al. (2002) Mga2p processing by hypoxia and unsaturated fatty acids in Saccharomyces cerevisiae: impact on LORE-dependent gene expression. Eukaryot Cell 1:481-90
Martin, C E; Oh, C-S; Kandasamy, P et al. (2002) Yeast desaturases. Biochem Soc Trans 30:1080-2
Kohlwein, S D; Eder, S; Oh, C S et al. (2001) Tsc13p is required for fatty acid elongation and localizes to a novel structure at the nuclear-vacuolar interface in Saccharomyces cerevisiae. Mol Cell Biol 21:109-25
Vasconcelles, M J; Jiang, Y; McDaid, K et al. (2001) Identification and characterization of a low oxygen response element involved in the hypoxic induction of a family of Saccharomyces cerevisiae genes. Implications for the conservation of oxygen sensing in eukaryotes. J Biol Chem 276:14374-84
Chellappa, R; Kandasamy, P; Oh, C S et al. (2001) The membrane proteins, Spt23p and Mga2p, play distinct roles in the activation of Saccharomyces cerevisiae OLE1 gene expression. Fatty acid-mediated regulation of Mga2p activity is independent of its proteolytic processing into a soluble transcription act J Biol Chem 276:43548-56
Jiang, Y; Vasconcelles, M J; Wretzel, S et al. (2001) MGA2 is involved in the low-oxygen response element-dependent hypoxic induction of genes in Saccharomyces cerevisiae. Mol Cell Biol 21:6161-9

Showing the most recent 10 out of 15 publications