Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM046495-04S1
Application #
2183985
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1991-07-01
Project End
1996-06-30
Budget Start
1994-07-01
Budget End
1995-06-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20817
Dunn, T M; Haak, D; Monaghan, E et al. (1998) Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain. Yeast 14:311-21
Garnepudi, V R; Zhao, C; Beeler, T et al. (1997) Serine palmitoyltransferase (scs1/lcb2) mutants have elevated copy number of the L-A dsRNA virus. Yeast 13:299-304
Beeler, T J; Fu, D; Rivera, J et al. (1997) SUR1 (CSG1/BCL21), a gene necessary for growth of Saccharomyces cerevisiae in the presence of high Ca2+ concentrations at 37 degrees C, is required for mannosylation of inositolphosphorylceramide. Mol Gen Genet 255:570-9
Beeler, T; Gable, K; Dunn, T (1997) Activation of divalent cation influx into S. cerevisiae cells by hypotonic downshift. J Membr Biol 160:77-83
Beeler, T; Bruce, K; Dunn, T (1997) Regulation of cellular Mg2+ by Saccharomyces cerevisiae. Biochim Biophys Acta 1323:310-8
Fu, D; Beeler, T J; Dunn, T M (1995) Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily. Yeast 11:283-92
Fu, D; Beeler, T; Dunn, T (1994) Sequence, mapping and disruption of CCC1, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants. Yeast 10:515-21
Zhao, C; Beeler, T; Dunn, T (1994) Suppressors of the Ca(2+)-sensitive yeast mutant (csg2) identify genes involved in sphingolipid biosynthesis. Cloning and characterization of SCS1, a gene required for serine palmitoyltransferase activity. J Biol Chem 269:21480-8
Beeler, T J; Gable, K S (1994) Phosphate, nitrendipine and valinomycin increase the Ca2+/ATP coupling ratio of rat skeletal muscle sarcoplasmic reticulum Ca(2+)-ATPase. Biochim Biophys Acta 1189:189-94
Dunn, T; Gable, K; Beeler, T (1994) Regulation of cellular Ca2+ by yeast vacuoles. J Biol Chem 269:7273-8

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