Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM046624-05
Application #
2184122
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1992-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Vermont & St Agric College
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405

  Publications

Harakall, S A; Brandenburg, C A; Gilmartin, G A et al. (1998) Induction of multiple pituitary adenylate cyclase activating polypeptide (PACAP) transcripts through alternative cleavage and polyadenylation of proPACAP precursor mRNA. Ann N Y Acad Sci 865:367-74
Flaherty, S M; Fortes, P; Izaurralde, E et al. (1997) Participation of the nuclear cap binding complex in pre-mRNA 3' processing. Proc Natl Acad Sci U S A 94:11893-8
Gilmartin, G M; Hung, S L; DeZazzo, J D et al. (1996) Sequences regulating poly(A) site selection within the adenovirus major late transcription unit influence the interaction of constitutive processing factors with the pre-mRNA. J Virol 70:1775-83
Graveley, B R; Gilmartin, G M (1996) A common mechanism for the enhancement of mRNA 3' processing by U3 sequences in two distantly related lentiviruses. J Virol 70:1612-7
Graveley, B R; Fleming, E S; Gilmartin, G M (1996) Restoration of both structure and function to a defective poly(A) site by in vitro selection. J Biol Chem 271:33654-63
Graveley, B R; Fleming, E S; Gilmartin, G M (1996) RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor. Mol Cell Biol 16:4942-51
Gilmartin, G M; Fleming, E S; Oetjen, J et al. (1995) CPSF recognition of an HIV-1 mRNA 3'-processing enhancer: multiple sequence contacts involved in poly(A) site definition. Genes Dev 9:72-83
Gilmartin, G M; Fleming, E S; Oetjen, J (1992) Activation of HIV-1 pre-mRNA 3' processing in vitro requires both an upstream element and TAR. EMBO J 11:4419-28