Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046770-05
Application #
2184264
Study Section
Molecular Biology Study Section (MBY)
Project Start
1992-02-01
Project End
1997-11-30
Budget Start
1996-02-01
Budget End
1997-11-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Nottoli, T; Hagopian-Donaldson, S; Zhang, J et al. (1998) AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice. Proc Natl Acad Sci U S A 95:13714-9
Shen, H; Wilke, T; Ashique, A M et al. (1997) Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds. Dev Biol 188:248-66
Creaser, P C; D'Argenio, D A; Williams, T (1996) Comparative and functional analysis of the AP2 promoter indicates that conserved octamer and initiator elements are critical for activity. Nucleic Acids Res 24:2597-605
Somasundaram, K; Jayaraman, G; Williams, T et al. (1996) Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2. Proc Natl Acad Sci U S A 93:3088-93
Bosher, J M; Totty, N F; Hsuan, J J et al. (1996) A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma. Oncogene 13:1701-7
Warren, G; Gordon, M; Siracusa, L D et al. (1996) Physical and genetic localization of the gene encoding the AP-2 transcription factor to mouse chromosome 13. Genomics 31:234-7