Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM046962-05
Application #
2184440
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1992-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Wang, Xiaoyan; Sheff, Mark A; Simpson, David M et al. (2011) Ste11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 gene. BMC Mol Biol 12:51
Elion, Elaine A (2006) Methods for analyzing MAPK cascades. Methods 40:207-8
Flotho, Annette; Simpson, David M; Qi, Maosong et al. (2004) Localized feedback phosphorylation of Ste5p scaffold by associated MAPK cascade. J Biol Chem 279:47391-401
Andersson, Jessica; Simpson, David M; Qi, Maosong et al. (2004) Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J 23:2564-76
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Wang, Yunmei; Elion, Elaine A (2003) Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components. Mol Biol Cell 14:2543-58
Elion, E A (2000) Pheromone response, mating and cell biology. Curr Opin Microbiol 3:573-81
Choi, K Y; Kranz, J E; Mahanty, S K et al. (1999) Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell 10:1553-68
Leza, M A; Elion, E A (1999) POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2. Genetics 151:531-43
Farley, F W; Satterberg, B; Goldsmith, E J et al. (1999) Relative dependence of different outputs of the Saccharomyces cerevisiae pheromone response pathway on the MAP kinase Fus3p. Genetics 151:1425-44

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