Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM047122-04
Application #
2184534
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1993-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Surgery
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Parker, M S; Sah, R; Park, E A et al. (2009) Oligomerization of the heptahelical G protein coupling receptors: a case for association using transmembrane helices. Mini Rev Med Chem 9:329-39
Parker, M S; Sah, R; Balasubramaniam, A et al. (2008) Dimers of the neuropeptide Y (NPY) Y2 receptor show asymmetry in agonist affinity and association with G proteins. J Recept Signal Transduct Res 28:437-51
Parker, Steven L; Parker, Michael S; Sah, Renu et al. (2008) Pertussis toxin induces parallel loss of neuropeptide Y Y1 receptor dimers and Gi alpha subunit function in CHO cells. Eur J Pharmacol 579:13-25
Parker, Steven L; Parker, Michael S; Wong, Ying Y et al. (2008) Importance of a N-terminal aspartate in the internalization of the neuropeptide Y Y2 receptor. Eur J Pharmacol 594:26-31
Parker, S L; Parker, M S; Sallee, F R et al. (2007) Oligomerization of neuropeptide Y (NPY) Y2 receptors in CHO cells depends on functional pertussis toxin-sensitive G-proteins. Regul Pept 144:72-81
Parker, S L; Parker, M S; Sah, R et al. (2007) Self-regulation of agonist activity at the Y receptors. Peptides 28:203-13
Balasubramaniam, Ambikaipakan; Mullins, Deborra E; Lin, Shu et al. (2006) Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity. J Med Chem 49:2661-5
Parker, M S; Sah, R; Sheriff, S et al. (2005) Internalization of cloned pancreatic polypeptide receptors is accelerated by all types of Y4 agonists. Regul Pept 132:91-101
Shahab, M; Balasubramaniam, A; Sahu, A et al. (2003) Central nervous system receptors involved in mediating the inhibitory action of neuropeptide Y on luteinizing hormone secretion in the male rhesus monkey (Macaca mulatta). J Neuroendocrinol 15:965-70
Sheriff, Sulaiman; Chance, William T; Iqbal, Sabahat et al. (2003) Hypothalamic administration of cAMP agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats. Peptides 24:245-54

Showing the most recent 10 out of 40 publications