Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM047332-04
Application #
2184738
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1992-05-01
Project End
1996-12-04
Budget Start
1995-05-01
Budget End
1996-12-04
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Vomastek, Tomas; Schaeffer, Hans-Joerg; Tarcsafalvi, Adel et al. (2004) Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists. Proc Natl Acad Sci U S A 101:6981-6
Eblen, Scott T; Slack, Jill K; Weber, Michael J et al. (2002) Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes. Mol Cell Biol 22:6023-33
Eblen, S T; Catling, A D; Assanah, M C et al. (2001) Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2. Mol Cell Biol 21:249-59
Gioeli, D; Zecevic, M; Weber, M J (2001) Immunostaining for activated extracellular signal-regulated kinases in cells and tissues. Methods Enzymol 332:343-53
Carson, J P; Kulik, G; Weber, M J (1999) Antiapoptotic signaling in LNCaP prostate cancer cells: a survival signaling pathway independent of phosphatidylinositol 3'-kinase and Akt/protein kinase B. Cancer Res 59:1449-53
Gao, Z; Chen, T; Weber, M J et al. (1999) A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. cross-talk between cyclic AMP and protein kinase c pathways. J Biol Chem 274:5972-80
Schaeffer, H J; Weber, M J (1999) Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol Cell Biol 19:2435-44
Chen, T; Cho, R W; Stork, P J et al. (1999) Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells. Cancer Res 59:213-8
Gioeli, D; Mandell, J W; Petroni, G R et al. (1999) Activation of mitogen-activated protein kinase associated with prostate cancer progression. Cancer Res 59:279-84
Schaeffer, H J; Catling, A D; Eblen, S T et al. (1998) MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science 281:1668-71

Showing the most recent 10 out of 29 publications