Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM047455-04
Application #
2184887
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1992-05-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Pathology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Maly, P; Thall, A; Petryniak, B et al. (1996) The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell 86:643-53
Smith, P L; Gersten, K M; Petryniak, B et al. (1996) Expression of the alpha(1,3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands. J Biol Chem 271:8250-9
Wagers, A J; Lowe, J B; Kansas, G S (1996) An important role for the alpha 1,3 fucosyltransferase, FucT-VII, in leukocyte adhesion to E-selectin. Blood 88:2125-32
Gersten, K M; Natsuka, S; Trinchera, M et al. (1995) Molecular cloning, expression, chromosomal assignment, and tissue-specific expression of a murine alpha-(1,3)-fucosyltransferase locus corresponding to the human ELAM-1 ligand fucosyl transferase. J Biol Chem 270:25047-56
Legault, D J; Kelly, R J; Natsuka, Y et al. (1995) Human alpha(1,3/1,4)-fucosyltransferases discriminate between different oligosaccharide acceptor substrates through a discrete peptide fragment. J Biol Chem 270:20987-96
Natsuka, S; Gersten, K M; Zenita, K et al. (1994) Molecular cloning of a cDNA encoding a novel human leukocyte alpha-1,3-fucosyltransferase capable of synthesizing the sialyl Lewis x determinant. J Biol Chem 269:16789-94
Mollicone, R; Reguigne, I; Kelly, R J et al. (1994) Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees. J Biol Chem 269:20987-94
Mollicone, R; Reguigne, I; Fletcher, A et al. (1994) Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6). J Biol Chem 269:12662-71
Lowe, J B (1993) The blood group-specific human glycosyltransferases. Baillieres Clin Haematol 6:465-92
Yago, K; Zenita, K; Ginya, H et al. (1993) Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines. Cancer Res 53:5559-65

Showing the most recent 10 out of 11 publications